One in ten Covid-19 patients who have diabetes and are hospitalised with the infection die within a week, study reveals
- Diabetes is one of the most high-risk conditions for severe Covid-19
- Study of 1,300 French hospital patients looked at outcomes after seven days
- Almost a third needed ventilation or died in that time frame. 18% went home
- Diabetics with common long-term complications had double the risk of death
One in ten Covid-19 patients who have diabetes and are hospitalised die within a week, a study has suggested.
Studies have repeatedly shown the condition is one of the high-risk conditions for developing a severe bout of the coronavirus.
French researchers looked at the outcomes of 1,300 hospitalised Covid-19 patients across the country, all of whom had diabetes.
Almost a third of them died or needed mechanical ventilation after seven days, the results revealed.
Diabetics with long-term complications of the disease affecting their blood vessels faced more than double the risk of death.

One expert claimed the bodies of diabetics may be slower at fighting any infections because key immune cells struggle to pass through their blood.
The study, published in the journal Diabetologia, is one of the first to analyse the effects of diabetes on hospitalised Covid-19 patients.
The majority (89 per cent) of patients had type 2 diabetes, which makes up most diabetes cases generally. It is linked with obesity and lack of exercise.
One in ten patients had died by day seven. The study did not follow up how many patients died overall.
Considering most of the patients arrived at hospital five days after their symptoms started, it means 10 per cent died in two weeks of getting infected.
One in five had been intubated and placed on a ventilator in intensive care within a week. The machines help a person to breathe when their lungs are failing.
For comparison, the average time to hospital admission to ventilation in the UK is 12 days, NHS data shows. It is not clear what proportion need it by day seven.
Separate figures suggest around 18 per cent of all patients hospitalised with Covid-19 spend time in intensive care.
More than half of those (58 per cent) receive 'invasive mechanical ventilation', according to available data.
Some 18 per cent of the French patients were discharged home by day seven.
Commenting on the findings, Duncan Young, professor of intensive care medicine, University of Oxford, said 'many more' are likely to have died after day seven.
He told MailOnline: 'On day seven... by far the majority were still in hospital at this point. The mortality of 10.3 per cent is very low and is only patients who died by day seven, many more would likely have died after.'
Encouragingly, there were no deaths in patients under 65 years old with type 1 diabetes, which the researchers said may reassure people with this type of diabetes.
However, they highlighted there were only 39 patients with type 1 diabetes in this study which is a small sample.
The study found that excess weight or common complications of the disease made matters worse.
Those with a higher body mass index (BMI) were more likely to reach the ‘end point’ - being either ventilated or dying by age seven.
But looking at death by day seven alone, there was no higher risk for heavier patients.
The presence of microvascular or macrovascular complications, which are when blood vessels are damaged by diabetes, more than doubled the risk of death at day seven.
Almost half of the hospitalised patients had microvascular complications when they were admitted, which affects small blood vessels like those in the eyes, nerves or kidneys have been blocked.
And 41 per cent had macrovascular complications, when bigger arteries that supply the heart, brain and legs are blocked.
Long-term complications of diabetes develop gradually and are exacerbated if a patient has poor sugar control.
Dr Hajira Dambha-Miller, a GP and specialist in diabetes, told MailOnline: 'Microvascular and macro vascular complications are a reflection of the severity of diabetes.
'It's why people with diabetes suffer with blindness, kidney failure and loss of sensation in the legs.
'If blood vessels are blocked by sugar, the body can't get blood around to where the immune cells are needed to fight off the virus. It's also slower at responding.
'Additionally, the long term high glucose damages the immune system so the immune cells don't work as well.'
But the study found a lack of sugar control itself was not a risk factor for Covid-19 death in one week.
Experts have warned that people with any form of diabetes should tightly manage their blood sugars – which is normal treatment anyway - because it will improve their outcomes should they catch the coronavirus.
There was also not link between high blood pressure in the diabetic patients and poor outcomes, even though hypertension has been found as one of the most prevalent underlying health condition in severe Covid-19 patients.
Men have been found to make up the most of Covid-19 fatalities but there was no gender differences in this group of patients, the researchers said.
Sarah Harper, a professor of gerontology at the University of Oxford told MailOnline, said the findings show similarities with our understanding of the impact of Covid 19 in the UK.
She told MailOnline: 'Being male, over 70, with a high BMI and diabetes, all increase the risk of becoming ill, needing intensive care and, sadly, dying from the Covid 19 disease.
'Indeed, these are all risk factors for increasing the likelihood of death from other causes.
'UK data shows that regardless of age, having diabetes doubles the risk of death from disease, though that risk is very small in the young and middle age.
‘Similarly is being overweight - so that a very overweight or obese British man in his early 60's has the same mortality risk - or chance of dying - as a slim man in his early 70's.
'And we know that being overweight increases your chances of getting type 2 diabetes.’
The findings also showed the sleep disorder sleep apnoea almost tripled the risk of dying after seven days, as did the presence of shortness of breath.
Dr Dambha-Miller said: 'We know that the virus affects the lungs and causes mass inflammation in there (called cytokine storm).
'If the lungs are already in bad shape, they won't do well once the virus enters the lungs.'
The authors plan to publish further work in the summer detailing outcomes of some 3,000 patients with diabetes hospitalised with COVID-19, looking at their status 28 days after admission to hospital.
A spokesperson for the NHS said: 'The risk from COVID-19 for people living with diabetes is clear, and the NHS has put extra plans in place to help people and keep them safe, including clinical guidelines for patients who are admitted to hospital, online sites to support people to care for themselves and a dedicated new helpline for advice and support.'
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